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INTERVENTIONAL TREATMENT OF TUMOURS

✅ Basic Concepts

  • The growth and division of cells in our organism is limited and this condition is regulated by genetic information transferred through chromosomes and interaction among the cells themselves.
  • A mass which is formed later and continued division of cells is called tumour.
  • The word tumour is of Latin origin and means a swelling, a small lump, a lump.
  • Tumours are divided into two groups and they may be benign and malignant.
  • Benign tumours do not generally recur in other organs and their growth can be stopped when the tumour reaches specific dimensions.
  • Malignant tumours, called cancer, continue dividing and multiplying and they tend to have metastases in other organs.
  • Tumours in one organism may be formed by almost all cells.
  • Some types of cancer (like small-cell lung cancer, pancreas cancer) may grow to large dimensions in a very short time and recur in other organs.
  • Cancer usually recurs through blood or lymph nodes, in adjacency. For example, the blood vessels of the colon transfer blood to the liver and that is why colon cancer gives most frequent recurrences in the liver.
  • Early diagnostics and treatment of tumours before they are able to form recurrences are of great significance.
  • The interaction and cooperation among the respective departments is a key factor in choosing the correct methods of treating tumours.

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                Liver tumour        After embolization

✅ Advantages of Interventional Treatment of Tumours

  • The procedures are usually performed under local anaesthesia and sedation.
  • The procedures are performed along with visualization of the tumour tissue.
  • Shorter stay in hospital.
  • The procedures are performed through a very small point – as big as a needle hole.
  • Fewer side effects.

✅ Interventional Methods of Treating Tumours

Embolization

  • This procedure is used for treating tumours by blocking arteries feeding the tumour.
  • The procedures are performed with the method of angiography.
  • A protector of the blood vessel is placed, usually through penetration from the pubic artery, followed by the insertion of a catheter with small tubes used for spraying blocking substances through the vein feeding the tumour.
  • Once the tumour tissue has lost feeding, it starts shrinking and disappears with time.

Basic Embolization

  • This procedure applies spraying very small microspheres into the blood vessel feeding the tumour.
  • It is most frequently applied with myomas, prostate tumours, and tumours of the musculoskeletal system.

Chemoembolization

  • The procedure is similar to the basic embolization. However, what makes it different is that this method does not only spray blocking microspheres in the veins but also chemotherapeutic drugs connected to them.
  • It is applied with liver tumours.

Radioembolization

  • This procedure applies spraying a radioactive drug attached to special microspheres directly into the arteries feeding the tumour tissue.
  • It is applied with liver tumours.

Treatment with Methods of Ablation

  • The dictionary meaning of the word ‘ablation’ is a process of removal and destruction of a part from the surface of a specific object.
  • It is a procedure of destruction through burning or freezing the tumour tissue through supplying different types of energy with special needles inserted into the tumour tissue.

Alcohol Ablation

  • It is applied for the destruction and elimination of the tumour tissue through penetration and insertion of special needles of pure alcohol in the tumour.
  • Nowadays, it is most frequently used for cystoid tumours.

Laser Ablation

  • This procedure applies destruction of tumour cells with laser rays.
  • It is applied mostly for nodules of thyroid gland.

Radiofrequency Ablation

  • This procedure applies burning the tumour tissue with special needles emitting radio waves.
  • It is most frequently used for tumours of liver, lungs, kidneys, and thyroid gland.

Microwave Ablation

  • This procedure is used for the destruction of the tumour tissue through special needles emitting electromagnetic waves.
  • It is most frequently used for tumour of liver, lungs, kidneys, and thyroid gland.

Cryoablation

  • This is a procedure of freezing the tumour tissue and destroying tumour cells with the help of special needles used for supplying gas – argon. 
  • It is most frequently applied with tumours of lungs, kidneys, breast, musculoskeletal system, and pancreas.